Noncoding sRNA Deemed Responsible for Onset of Periodontitis

Effect of Systemically Administered Azithromycin in Early Onset Aggressive Periodontitis

Azithromycin is a macrolide which possesses a strong antimicrobial activity against Gram-positive and Gram-negative pathogens. In the present study, we studied the effect of azithromycin as an adjunct to non-surgical treatment in early onset aggressive periodontitis. Initial treatment consisting of oral instructions and full-mouth scaling and root planing was performed over a 2-month period. Pa...

Early-onset periodontitis: progression of attachment loss during 6 years.

We studied the pattern of progression of early-onset periodontitis and the change in the extent and severity of the periodontal condition in adolescents who were followed for 6 years. In a national survey of the oral health of U.S. children, 14,013 adolescents were examined clinically in 1986/1987 to assess the periodontal attachment loss of teeth. Individuals with early-onset periodontitis wit...

Second Symposium Deemed a Success

Experiments were performed on cultured Chinese hamster ovary cells exposed to haematoporphyrin derivative (HpD) plus light, yielding survival rates of 40-100%. [3H]-thymidine, [3H]-tryptophan and ['4C]-lysine incorporation were used to quantitate DNA and protein synthesis in surviving cells after exposure. Multiple experiments demonstrated 78% reduction in DNA sysnthesis during the first day af...

The measurement Einstein deemed impossible

Neutrophil migration, oxidative metabolism and adhesion in early onset periodontitis.

The aim of this study was to evaluate neutrophil function in patients suffering from the generalized form of early onset periodontitis (EOP). We investigated neutrophil migration in vivo and neutrophil superoxide production and adhesion in response to a variety of compounds; neutrophils were isolated both from blood and a skin experimental exudate of 15 patients with EOP and of 15 sex- and age-...